A Move to Draw Attention


In a move that could draw attention from the world’s top cardiac device makers, researchers in Korea have developed a self-powered artificial cardiac pacemaker that operates without battery power. A team from the Korea Advanced Institute of Science and Technology (KAIST) designed a cardiac pacemaker implant that runs on a piezoelectric nanogenerator, rather than traditional batteries. Pacemaker batteries typically last seven years on average, and require frequent replacements by putting patients at risk for infections or severe bleeding during operations, Medical Xpress reports. The flexible nanogenerator from South Korean researchers directly stimulated a living rat’s heart using electric energy converted from small body movements, forgoing the need for battery replacement. “For clinical purposes, the current achievement will benefit the development of self-powered cardiac pacemakers as well as prevent heart attacks via the real-time diagnosis of heart arrhythmia,” lead researcher Professor Keon Jae Lee told Medical Xpress. “In addition, the flexible piezoelectric nanogenerator could also be utilized as an electrical source for various implantable medical devices.”  The discovery comes in the midst of industry innovation, as devicemakers compete to develop the most cutting-edge pacemaker product. Earlier this month, the Minneapolis-based device giant implanted its tiny leadless cardiac pacemaker in its first patients as part of a global clinical trial, eyeing the regulatory finish line with promising single-arm study results.  The Korean hot line failed to compile statistics on nationality, but it is reasonable to assume most would have been Korean. The Korean hot line did compile statistics on age, and found that 80% of the comfort women were between the ages of 14 and 18.

Keon Jae Lee

However, given that the hot line was opened in 1992, it seems likely that the statistics are skewed towards younger women. Aside from recruitment by Army agents in Japan and Korea, there was recruitment by the Kempeitai from Dutch women in internment camps, recruitment through village headmen in the Netherlands, and recruitment by individual Army units in the Philippines. Recruitment in the Philippines seems to have been particularly violent, often taking the form of a woman being kidnapped and raped, then taken to a military installation to be gang raped by members of the local unit. However, this pattern fell outside the normal comfort system. Although early recruitment was mostly carried out by private agents hired by the Army, direct recruitment by the Army became more common later in the war, and was often carried out under the cover of wartime labor mobilization. Since the kempeitai had long enforced licensed prostitution in Korea, it seems likely they were involved in direct recruitment of comfort women here as well. Mistreatment of Korean comfort women was one of the main problems. Many surviving comfort women testify of appalling treatment. Some were forced to have sex with as many as 50 men per day.

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Detection of 150 Genetic Syndromes Via Amniochip



Genetadi Biotech has introduced to established researchers – meeting at the XXVI National Congress on Human Genetics held in Murcia – a pre-birth indicative gadget focused around amniocentesis. All the more solidly, it is focused around microarray engineering and with an analytic determination 100 times more noteworthy than the normal cytogenetic strategies. The new gadget, known as Amniochip, has the capacity identify 150 hereditary syndromes. “This involves currently validated genetic syndromes, including malformations and idiopathic mental deficiency not detected with a conventional kariotype”, explained Ms Silvia Ávila, co-director of Genetadi. The researchers brought up that one of the favorable circumstances of this imaginative system is the way that a cell culture is not necessary. Accordingly, the holding up time for the results with the new gadget drops to 48 hours, rather than the three weeks it as of now takes through customary kariotype strategy. In any case, from a clinical point of view, the system for the conclusion does not differ, beginning with a standard amniocentesis embraced by the expert gynecologist. “The sample of amniotic liquid does not differ at all from the current amniocentesis procedure”, explained doctor Ávila. “With the Amniochip only 8 or 10 ml of amniotic liquid are necessary in a tube, and which is sent to a laboratory via messenger, exactly as with the usual genetic trials”. The application of this new engineering, through a remedy from the pro in gynecology and obstetrics, is particularly suitable for each one of those pregnant ladies who oblige a customary hereditary study. That is, those associated from ecographs with having malformations, or with positive triple marker, or the in excess of 35s. It is likewise suitable for couples with a history of unsuccessful labor, or with a family history of hereditary disorders.

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Latest Medical Breakthrough for the Heart

person who has heart attack

Heart disease is the main executioner on numerous nations these days. This year, heart specialists was able to figured out how to do something awhile ago thought practically incomprehensible: Using the most extreme measurements of the cholesterol-bringing down solution Crestor, they found themselves able to psychologist the greasy stops up blocking heart patients courses by around 7 percent in excess of two years. The finding is critical in light of the fact that its generally been accepted that atherosclerosis, the development of plaque in the corridors, was irreversible, says creator Steven Nissen, MD, head of cardiovascular prescription at the Cleveland Clinic and president of the American College of Cardiology. Previously, the best you could plan to do with medications or a sound way of life was moderate or stop the slow narrowing despite the fact that an angioplasty or stent can open up blocked courses. The new discovering raises the likelihood that you can really turn around the plaque gathering that begins as ahead of schedule as adolescence. It likewise powers the developing acknowledgment that dropping LDL, or awful, cholesterol to levels far beneath the 100 milligrams for every deciliter that’s considered ideal is the most ideal approach to avert heart assaults (the study members decreased theirs from 130 to 61). Current rules exhort that just individuals at high danger of a heart assault go for a LDL level underneath 70, however Nissen says its conceivable that some time or another even those at lower danger will basically shoot for the least cholesterol number thats securely conceivable.

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Areas that Control Anxiety

person experiencing anxiety

New optogenetic research on mice from Karl Deisseroth’s lab at Stanford has recognized two imperative pathways identified with anxiety control in the cerebrum. The lab has spearheaded a method that hereditarily alters particular cells to end up more dynamic when light is presented. Along these lines the scientists have the capacity pinpoint which cells are included with a particular cerebrum action. From National Science Foundation’s press discharge, coordinated hereditary controls cause particular neurons to collect a light-actuated protein typically found in green growth and microscopic organisms. At the point when activated by specific wavelengths of light, these proteins permit specialists to expand or diminishing neuronal movement in the mind and watch the consequences for rat models in an investigation. Utilizing optogenetic control of different amygdala pathways, Deisseroth and associates inspected how mouse conduct was influenced. Since mice show uneasiness related practices in open spaces, they measured changes in tension by breaking down the amount of time mice used investigating the focal point of an open field, or investigating the length of a stage without dividers. While optogenetics has been utilized to study amygdala work in behaviorally-molded alarm. It is also the first occasion when it has been utilized to study nervousness. “Fear and anxiety are distinctive,” Deisseroth clarified. “Fear is a response to an immediate threat, but anxiety is a heightened state of apprehension with no immediate threat. They share the same outputs, for example physical manifestations such as increased heart rate, but their controls are very different.”

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Functional Dopaminergic Neurons

Person with Parkinson’s Disease

Parkinson’s disease is an element neurodegenerative issue stamped by the loss of dopamine-conveying neurons in the brain and since dopamine is incorporated in the regulation of improvement and energetic impact, the loss of these neurons prompts deficiencies in motor activity and enthusiastic response. Cell medicines that intend to restore lost dopaminergic neurons hold ensure for directing the development of Parkinson’s. Investigators from Lund University in Sweden have dispersed an article in Cell Stem Cell depicting the time of utilitarian dopaminergic neurons from human embryonic juvenile microorganisms. Headed by Prof. Malin Parmar, the gathering divided dopaminergic neurons from human embryonic foundational microorganisms in the public arena, then transplanted them into the brains of rats that were exhibited to show the evidences of Parkinson’s. Prof. Parmar and partners exhibited that after transplantation, the embryonic undifferentiated cell decided dopaminergic neurons demonstrated the utilitarian characteristics of neighborhood dopaminergic neurons, including dopamine era and furthermore long partition development and relationship with target regions in the brain. Given that there is at this time no cure for Parkinson’s contamination and that meds and significant cerebrum impelling can be diminished symptoms yet not temper infection development, the current study is seen as an accomplishment. Not at all like fetal undeveloped cells, which have been long back used to make dopaminergic neurons, embryonic undifferentiated creatures offer a bountiful, instantly open supply of cells. As a rule, the results of this study display a basic preclinical check of thought, with a normal time to human trials set for about 3 years.

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Synthetic Platelets to Heal Wounds

Synthetic Platelet

Basic wound recuperating has been progressed with an engineered platelet that gathers at destinations of harm, clusters and quits draining three times speedier. The engineered platelets have reasonable size, plate shape, adaptability, and the same surface proteins as genuine platelets. Fake platelets made by the University of California and Case Western Reserve University have been indicated to stop draining in mouse explores much speedier than nature can all alone. Shockingly, they have possessed the capacity to integratively emulate the shape, size, adaptability and surface science of true blood platelets on egg whites based molecule stages. The specialists accept these four outline considers together are key for instigating clusters to structure speedier at vascular damage locales while keeping unsafe clumps from framing somewhere else in the body. The new engineering, reported in the diary ACS Nano, is gone for stemming draining in patients experiencing traumatic harm, experiencing surgeries or experiencing coagulating issue platelet deformities or an absence of platelets. Further, it could be utilized to convey medications to target destinations in patients enduring atherosclerosis, thrombosis or other platelet-included pathologic conditions. Anirban Sen Gupta, partner educator of biomedical building at Case Western Reserve, awhile ago composed peptide-based surface sciences that copy the coagulation applicable exercises of true platelets. Expanding on this work, he now concentrates on fusing morphological and mechanical prompts that are regularly display in platelets to further refine their configuration. Morphological and mechanical elements impact the margination of characteristic platelets to the vein divider, and just when they are close to the divider can the discriminating coagulation advancing substance associations occur.

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PACS and Breast Imaging

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Supports PACS and breast imaging in color and grayscale

On 16 October 2014, healthcare visualization expert Barco announces the release of Coronis Uniti, the first diagnostic display explicitly designed for both PACS and breast imaging. Lynda Domogalla, Vice President of product marketing for Barco’s Healthcare division, said that with nearly 30 years of experience in healthcare imaging, we understand the radiology market and the challenges the industry is facing today. It’s this experience that led to the development of Coronis Uniti, a diagnostic display system that unifies the workflow for radiologists. Coronis Uniti has a unique representation of calibrated color and grayscales. It is remarkable in its 2D and 3D capabilities and capable of both static and dynamic imaging. It combines PACS and breast images on one workstation, pushes productivity and speeds up reading sessions.  Every Coronis Uniti display is calibrated to meet the DICOM standard for grayscales and to guarantee consistent, perceptually linear color so everything that will be seen on the big, 12 MegaPixel screen is sharp and precise. It is designed with ergonomics in mind, mirroring a human’s natural field of vision to optimize your reading experience. It reduces reflection, enhances image sharpness, reduces eye fatigue, Limits head, hand, and eye movements and increases reading comfort. It will help to see more patients per day, simplifies control and management of the display network and leads to major reductions in display cost. Coronis Uniti has technologies that enhance productivity such as RapidFrame to ensure crisp and in focus moving images, touchpad for faster control and smooth image manipulations, Ambient Light Compensation.

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A Cancer Detection Device

detect and monitor disease

Using Miroculus kit, a simple blood test can tell you, at the molecular level, the exact type of disease you have and its severity before presenting any symptoms. Using the same test, the success of the treatment will be monitored. Miroculus detect and monitor disease at the molecular level in three steps and it is accurate, easy to use, non-invasive, decentralized, operator independent and affordable microRNA detection platform for molecular data gathering, analysis and interpretation. Let me discuss the three steps I have said earlier. First is the microRNA profiling, it extracts the total RNA from the patient’s blood sample and pipette it in a standard 96 well plate. Without the need of a specialized technician or expensive lab machinery, the proprietary chemistry in it can detect microRNAs from body fluids or tissue. Each well of this plate has patented biochemistry is looking for a specific microRNA. This biochemistry  acts like a trap that closes when the microRNA is present in the sample and when a trap closes, green color will shine.  Second is it will prepare and load the 96 well plate in the device. the device will make microRNA detection more affordable than ever. We need to wait for about 60 minutes for the reaction to run. Your smartphones is the one that will process the results, match the wells that shine with specific microRNAs and analyze how much and how fast they shine. This will tell us whether the microRNAs that are present in the sample are over-regulated or down-regulated. The last step is to login to visualize the patient’s results. You can get the results in real time.

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Talk With A Deaf Person Anytime And Anywhere

Diagram on how Transcense works

According to studies, five percent of the world population suffers from disabling hearing loss, and struggle to follow conversations especially in groups. It’s really hard to read lips in group situations. Only 25 percent of English can be read on lips. You may have missed a change of topic and end up confused if you miss a few words due to change of speakers. Transcense is the first mobile app that makes group conversations between deaf and hard of hearing people and their hearing peers, finally possible and effortless.In real time, it shows you who says what around you and in result, you can answer in time and be part of the discussion. Transcense will not let you miss a conversation again. It will transcribe a group conversation such as a business meeting, a family dinner, or a moment with friends. It connects to multiple smartphones and leverages their microphones to listen and to interpret the convesation right into the participants screen.For those who’s having hearing disabilities to understand discussions, this will be your affordable personal interpreter for group communications anytime and everywhere. You wouldn’t bring an interpreter or a captioner to a date, lunch or family gathering because Transcense can be your private companion that will give you privacy and information. The developers  of Transcense technology worked on this for over a year, they have talked to more than 300 audiologists, deaf, hard of hearing, seniors, speech and behavioral design expert to help design the solution to this problem. It is now in private Beta on Android.

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BodyEcho, A Serious Sleep Tracking Device

BodyEcho Vitals Monitor for More Advanced Sleep Tracking (VIDEO)


Other Sleep devices and applications may only measure your movement in bed, BodyEcho offers the most accurate and powerful sleep tracking solution available. It uses advanced sensor technology to give you clear insights into sleep stages, unconscious disturbances in you sleep, sleeping position, interruption of breathing, changes in blood oxygen saturation, tossing and turning, heart rate and snoring. You can develop better sleeping habits that will allow you to feel more energized and healthful by using the BodyEcho. You sleep data will be displayed as an easy to understand mobile app and companion web portal, listening to your body- even while your mind rests. Hyperachievers, parents, grandparents, even plugged-in teenagers or everyone who wants to take true control of their sleep can all benefit. You just need to follow four easy steps to use BodyEcho. First is to place the BodyEcho headband on, next is to set the smartphone app to “Sleep Mode” then sleep and when you wake up, the BodyEcho will have your sleep analysis waiting for you. BodyEcho has a tiny sensor that brings oximetry, heart rate, motion, temperature and respiratory rate all together.Combining oxygen with more commonly-tracked factors enables you to better analyze your sleep quality, track any disturbances and understand the stages of sleep. What’s unique about the BodyEcho is, at the core of it, is a laboratory grade oximeter which measures your heart rate and oxygen level to the highest degree of precision available in consumer sleep sensors, combining it with an accelerometer which senses both small vibrations as snoring and larger movements like turning from side to side.

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